Dr. Keyes was born in Wareham, Massachusetts. She attended Wheaton College in Norton, Massachusetts, where she received her B.A. in Chemistry and Biochemistry. She received her medical degree from Georgetown University School of Medicine, Washington, D.C. She completed her medical training in Internal Medicine and Cardiology at the University of Pittsburgh Medical Center in Pittsburgh, Pennsylvania.

Prior to joining Cardiovascular Medicine, Dr. Keyes served as the Director of the Anticoagulation Clinic and the Director of the Women's Heart Center at Ohio Heart Care, Inc., Canton, Ohio. She joined Cardiovascular Medicine in 1997.

Among her many professional memberships are the American Medical Association, the American College of Cardiology, the Council on Clinical Cardiology of the American Heart Association, the American Society of Echocardiography, and the American Society of Nuclear Cardiology.​

She is licensed to practice medicine in both Iowa and Illinois and is available for outpatient consultation and follow up visits at the Davenport location. She has staff privileges at Genesis Medical Centers and UnityPoint Health Trinity. She is board certified in Cardiovascular Disease. She currently serves as Medical Director of Cardiac Diagnostics at Cardiovascular Medicine and Medical Director of Diagnostic Services and Cardiopulmonary Rehab at Genesis Medical Center.